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Retinol: benefits, uses and mistakes to avoid

Elsa Dargier
22/08/2025
Rétinol : bienfaits, utilisation et erreurs à éviter

You hear about it everywhere: on social media, in your favorite anti-aging skincare products, in dermatologist recommendations. Retinol has established itself as one of the most powerful ingredients in modern cosmetics. And for good reason: it promises smoother, more radiant skin, less marked by wrinkles or imperfections. But behind its many benefits , a few precautions are necessary to avoid irritation, redness, and poor combination with other active ingredients. We take a look in this article.

What is retinol?

Retinol is a form of vitamin A used in cosmetics to stimulate cell renewal. It is part of a family of active ingredients called retinoids , all of which have proven effectiveness on skin aging, pigment spots, and acne. Retinol is popular because it is less irritating than retinoic acid , while remaining powerful enough to deliver visible results.

Retinol exists in different forms:

  • Pure retinol : Most commonly found in creams and serums. It is effective but can cause irritation.

  • Retinaldehyde : more active, but also more expensive. It is better tolerated by some skin types.

  • Retinoic acid : very effective, this is an active form available on medical prescription only (e.g.: Tretinoin)

  • Retinol esters (e.g. retinyl palmitate): These are much milder, but also less potent.

What are the benefits of retinol for the skin?

Retinol is one of the only cosmetic active ingredients whose effects have been validated by numerous scientific studies*. It acts on several aspects of skin aging and common skin disorders.

  • Reduction of fine lines and wrinkles : by stimulating the production of collagen and elastin, retinol plumps the skin and smoothes wrinkles

  • Evenness of complexion : it reduces pigment spots linked to the sun, age or acne scars

  • Refined pores and skin texture : thanks to its gentle exfoliating effect, it gives a smooth skin effect

  • Reduction of pimples and blackheads : by regulating sebum production and unclogging pores, it is useful against adult acne

  • More radiant complexion : by accelerating cell renewal, it revives dull and tired skin

It is therefore a multi-function treatment: anti-aging , anti-dull complexion and anti-blemish !

At what age can you use retinol?

Retinol isn't just for mature skin! It can be incorporated into a beauty and anti-aging routine. from the end of the twenties , provided you choose the right concentration and frequency of application.

  • From the age of 25-30 , it helps prevent the first signs of aging, smooth skin texture, and avoid expression lines.

  • From the age of 35-40 , it targets established wrinkles, spots and loss of firmness

  • In younger people (18-25 years old), retinol may be prescribed by a dermatologist to treat resistant acne or acne scars

Its use is therefore not a question of age , but of objective and skin type!

How to use retinol properly? Precautions to follow

Retinol is a powerful active ingredient that can cause redness, tightness, or peeling if used incorrectly. To avoid adverse effects, follow these essential steps:

  • Integrate it gradually : start with 1 to 2 times a week, in the evening, on dry, clean skin

  • Moisturize your skin well : Use a nourishing cream after applying retinol to strengthen the skin barrier

  • Use sunscreen every morning : retinol makes skin more sensitive to the sun

  • Avoid combining it with certain irritating active ingredients (fruit acids, exfoliants, concentrated vitamin C, etc.) in the same routine

  • Avoid the eye area , unless the treatment is specifically formulated for this delicate area

  • Be patient : the first visible effects generally appear after 4 to 6 weeks, but more marked results (wrinkles, radiance, spots) may require 3 to 6 months of regular use

In summary, retinol can be suitable for most skin types, but it is advisable to start gradually , especially if you have sensitive or redness-prone skin. Low-concentration or time-release formulas are recommended for reactive skin.

Please note : Retinol and other retinoids are not recommended during pregnancy and breastfeeding, even for topical use. It is better to turn to natural alternatives such as bakuchiol.

How to choose the right retinol treatment?

It's not easy to find your way around facial serums , creams, concentrations and types of retinol... Here are some tips to help you choose:

  • For beginners : Choose a product with 0.1% to 0.3% retinol

  • For regulars : you can increase to 0.5% or 1%, if your skin tolerates the active ingredient well.

  • Encapsulated formulas : they allow a gradual release of retinol, for greater tolerance

  • Cream or serum? Choose according to your skin type:

    • Combination to oily skin: choose a light retinol serum

    • Dry or sensitive skin: choose a nourishing cream

Also look for the presence of soothing ingredients (niacinamide, ceramides, hyaluronic acid) in the formula.

Are there natural alternatives to retinol?

Yes, and the best known is bakuchiol . This plant active ingredient extracted from the Psoralea corylifolia plant is a gentle alternative to retinol.

  • It has comparable effectiveness on skin elasticity and radiance (according to some studies)

  • It does not cause irritation or sensitivity to the sun

  • It is compatible with pregnancy (unlike retinol)

Other gentle but less powerful options also exist:

  • Rosehip oil

  • Provitamin A (beta-carotene) in carrot oil

  • New generation retinoids (such as granactive retinoid)

What can you mix retinol with?

Although powerful, retinol can be combined with other active ingredients if certain guidelines are followed. For example, retinol works very well in combination with hyaluronic acid, which hydrates and soothes the skin, helping to better tolerate retinol. You can apply it before or after your retinol treatment.

Here is a table with the most common assets to help you:

Active

Compatible with retinol?

Recommendation for use

Hyaluronic acid

Yes

Apply immediately after or mix with the treatment to soothe

Niacinamide

Yes (ideally 1-5%)

Promotes tolerance and strengthens the skin barrier

Vitamin C

Yes, but not together

Vitamin C in the morning, retinol in the evening

AHA/BHA (acids)

To avoid together

Use alternately (e.g. acids on Monday, retinol on Wednesday)

Peptides

Yes

Complementary anti-aging action without irritation

Always test gradually , and only introduce one new active ingredient at a time into your routine to monitor your skin's tolerance.

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* Kafi et al., 2007 — Archives of Dermatology

“Improvement of naturally aged skin with vitamin A (retinol)”

Mukherjee et al., 2006 — Clinical Interventions in Aging

"Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety"

Oresajo et al., 2012 — Journal of Cosmetic Dermatology

“Clinical effects of retinol”.